While the Lesser Carpathians / Malokarpatská region close to the Austrian border is the oldest wine region in Slovakia, Južnoslovenská would be the warmest Slovak region, resulting in more riper wine styles

Located in the lowlands north of the Danube (which also serves as the Slovak-Hungarian border), the region has eight viticultural areas and 114 villages. Vineyards are found on the clay-rich plains and for the newer plantings, on the loess-rich uplands and alluvial terraces by the riverside.

This is the warmest Slovak region with an effective accumulated temperature of over 3400°C during the growing season (higher than all other regions) and 2,200 hours of sunshine per year.

While white grapes such as Veltlinske Zelené and Rizling Vlašský are among the most planted varieties, Frankovka Modrá, Pinot Noir and late-ripening grapes such as Cabernet Sauvignon are also cultivated here.